Comparison of post operative findings dexmedetomidine versus fentanyl as adjuvant to levobupivacaine heavy in spinal anesthesia for total knee replacemnent

Comparison of post operative outcome of levobupivacaine with dexmedetomidine and levobupivacaine vs fentanyl as adjuvant in patients undergoing total knee replacement under spinal anesthesia. - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/110835

Enrollment

100

Registered

2026-05-21

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: nil: nil Control Intervention1: levobupivacaine heavy with fentanyl vs levobupivacaine heavy dexmedetomidine.: following postoperative outcome will be evaluated 1-sedation 2-nausea and

Eligibility

Inclusion criteria

Inclusion criteria: ASA PHYSICAL STATUS I & II WEIGHT 60-90 UNILATERAL TOTAL KNEE REPLACEMENT SURGERIES

Exclusion criteria

Exclusion criteria: PATIENT REFUSAL LOCAL INFECTION AT DRUG INFILTERATION SITE COAGULOPATHY AND BLEEDING DISORDER ASA MORE OR EQUAL TO 3

Design outcomes

Primary

Measure	Time frame
REQUIREMENT OF RECUE ANALGESIA, VAS SCORING TIME OF POST OP AMBULATIONTimepoint: FOR 24 HOURS	—

Secondary

Measure	Time frame
POST OPERATIVE SEDATIONTimepoint: FOR 24 HOURS;POST OP NAUSEA AND VOMIINGTimepoint: FOR 24 HOURS;POST OP SHIVERINGTimepoint: FOR 24 HOURS ;POST OPERATIVE TIME TO MICTURITION AND NEED OF CATHERISATIONTimepoint: FOR 24 HOURS;POST OPERATIVE HEMODYNAMICSTimepoint: FOR 24 HOURS;ONSET TIME OF SENSORY AND MOTOR BLOCKTimepoint: ;MAXIMUM BROMAGE SCORE ACHIEVED AND TIME TO ACHIEVE THATTimepoint: ;HEMODYNAMIC STABILITYTimepoint: NIL	—

Measure

Time frame

POST OPERATIVE SEDATIONTimepoint: FOR 24 HOURS;POST OP NAUSEA AND VOMIINGTimepoint: FOR 24 HOURS;POST OP SHIVERINGTimepoint: FOR 24 HOURS ;POST OPERATIVE TIME TO MICTURITION AND NEED OF CATHERISATIONTimepoint: FOR 24 HOURS;POST OPERATIVE HEMODYNAMICSTimepoint: FOR 24 HOURS;ONSET TIME OF SENSORY AND MOTOR BLOCKTimepoint: ;MAXIMUM BROMAGE SCORE ACHIEVED AND TIME TO ACHIEVE THATTimepoint: ;HEMODYNAMIC STABILITYTimepoint: NIL

—

Countries

India

Contacts

Public ContactDr rps sibia

government medical college patiala

amankharbanda56@gmail.com9876090737

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026