Health Condition 1: I25- Chronic ischemic heart disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 Undergoing CABG without any valvular abnormalities 2 Age been 60 and 75 years 3 Elective CABG for CAD (DVD, TVD) 4 LVEF more than 40% 5 No significant valvular abnormality. 6.Both genders
Exclusion criteria
Exclusion criteria: Other associated structural cardiac abnormalities. 1 LVEF less than 40% 2 Preoperative inotropes 3 Mechanical ventilation 4 Emergency CABG 5 Moderate or severe MR, TR, AS, AR 6 Known allergy to the local anesthetic drug used in the procedure. 7 Inability to comply with study requirements
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the incidence of Post induction Hypotension in Frail vs Non-Frail patients.Timepoint: t1 is at baseline readings t2 is after fentanyl and midazolam t3 is at BIS less than 90 t4 just before induction t5 is at 1 min after induction t5 is at 3 min after induction | — |
Secondary
| Measure | Time frame |
|---|---|
| To find Incidence of MAP less than 65 mm Hg at BIS less than 50 after induction 2The Maximum percentage decrease in MAP from baseline within 15 minutes of anaesthetic induction with EtomidateTimepoint: 15 minutes | — |
Countries
India
Contacts
Army Hospital (Research and Referral), Delhi.