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Observational study to find association between pre-operative frailty and hypotension after anesthesia induction

Association of PRE-OPERATIVE FRAILITY ON HEMODYNAMIC RESPONSE TO ETOMIDATE INDUCTION IN PATIENTS UNDERGOING ELECTIVE CABG USING HEMODYNAMIC MONITORING - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/05/110803
Enrollment
120
Registered
2026-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I25- Chronic ischemic heart disease

Interventions

Intervention1: Nil: Nil

Sponsors

KALPNA BHARDWAJ
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Undergoing CABG without any valvular abnormalities 2 Age been 60 and 75 years 3 Elective CABG for CAD (DVD, TVD) 4 LVEF more than 40% 5 No significant valvular abnormality. 6.Both genders

Exclusion criteria

Exclusion criteria: Other associated structural cardiac abnormalities. 1 LVEF less than 40% 2 Preoperative inotropes 3 Mechanical ventilation 4 Emergency CABG 5 Moderate or severe MR, TR, AS, AR 6 Known allergy to the local anesthetic drug used in the procedure. 7 Inability to comply with study requirements

Design outcomes

Primary

MeasureTime frame
To compare the incidence of Post induction Hypotension in Frail vs Non-Frail patients.Timepoint: t1 is at baseline readings t2 is after fentanyl and midazolam t3 is at BIS less than 90 t4 just before induction t5 is at 1 min after induction t5 is at 3 min after induction

Secondary

MeasureTime frame
To find Incidence of MAP less than 65 mm Hg at BIS less than 50 after induction 2The Maximum percentage decrease in MAP from baseline within 15 minutes of anaesthetic induction with EtomidateTimepoint: 15 minutes

Countries

India

Contacts

Public ContactJosemine Davis

Army Hospital (Research and Referral), Delhi.

bhargavadv@gmail.com8135855155

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026