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A Study of a Natural Method for Male Cell Selection

Comparison of Cumulus Cell Columnâ??Based Sperm Selection Versus Conventional Double Density Gradient Preparation in ICSI Cycles: A Prospective Sibling Oocyte Study Evaluating Sperm DNA Integrity and Embryo Developmental Competence. - Not applicable

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110768
Enrollment
104
Registered
2026-05-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N469- Male infertility, unspecified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

OASIS FERTILITY India
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Male partner providing fresh ejaculate sample for ICSI Semen concentration Greater than 10 million per mL Male age 22 to 45 years Female age less than 38 years Greater Than 12 mature MII oocytes retrieved

Exclusion criteria

Exclusion criteria: Severe male factor infertility as per World Health Organization 2021 criteria Donor gamete cycles Severe male factor infertility as per WHO 2021 criteria Known sperm DNA Fragmentation Index Greater than 30% if pre-tested Surgically retrieved sperm TESA PESA micro-TESE Less than 12 MII oocytes retrieved Sero discordant highrisk infected couples

Design outcomes

Primary

MeasureTime frame
Blastocyst formation rateTimepoint: 01 Year—

Secondary

MeasureTime frame
Fertilization rate Cleavage rate Blastocyst quality based on Gardner grading Cycle cancellation rate no blastocyst formation Change in sperm DFI across processing methods Timepoint: 01 Year—

Countries

India

Contacts

Public ContactDr Krishna Chaitanya Mantravadi

OASIS FERTILITY

krishna@oasisindia.in8008812999

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026