Comparision of spinal anesthesia techniques for maintaining blood pressure in elderly patients during lower limb surgery

Effects of Dose Fractionation and Delayed Positioning on Post spinal Vasopressor Requirement in elderly patients undergoing lower limb surgeries: A three-arm Randomized controlled trial. - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/110760

Enrollment

Registered

2026-05-21

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M800- Age-related osteoporosis with current pathological fracture Health Condition 2: M849- Disorder of continuity of bone, unspecified

Interventions

Intervention1: Group F: Fractionated Group patients will be administered a fractionated dose of 3ml (15 mg) Bupivacaine with two third dose that is 10 mg given initially the syringe will be kept att

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age group: more than 60 years of age posted for elective lower limb orthopaedic surgeries 2. ASA physical status I,II and III

Exclusion criteria

Exclusion criteria: 1.Patient refusal 2.Localised infection at the injection site 3.Allergic to local anaesthetic drugs 4.Increased ICP 5.Relative spinal contraindications such as Myelopathy or Peripheral neuropathy, Spinal stenosis, Spina Bifida, Multiple sclerosis, Aortic stenosis, Hypovolemia, Hereditary coagulopathies.

Design outcomes

Primary

Measure	Time frame
To compare Intraoperative Vasopressor (Ephedrine) Requirementpost spinal anesthesia in Conventional, Fractionated and Delayed group.Timepoint: 24 hours	—

Secondary

Measure	Time frame
1. To compare Post Spinal hemodynamic Mean Arterial Pressure and Heart Rate changes during 1st hour. 2. To evaluate onset of motor and sensory blockade. 3. To compare highest level of sensory blockade. 4. To compare duration of sensory and motor blockade. 5. To assess the Intraoperative Fluid Requirement. 6. To assess the complications (nausea and vomiting, chills, urinary retention, and itching).Timepoint: 24 hours	—

Measure

Time frame

1. To compare Post Spinal hemodynamic Mean Arterial Pressure and Heart Rate changes during 1st hour. 2. To evaluate onset of motor and sensory blockade. 3. To compare highest level of sensory blockade. 4. To compare duration of sensory and motor blockade. 5. To assess the Intraoperative Fluid Requirement. 6. To assess the complications (nausea and vomiting, chills, urinary retention, and itching).Timepoint: 24 hours

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Countries

India

Contacts

Public ContactDR SHIVANAND Y HULKUND

S Nijalingappa Medical College and HSK Hospital

hulkunds@yahoo.com9901098533

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026