Health Condition 1: J80- Acute respiratory distress syndrome
Conditions
Interventions
Intervention1: intervention group will receive standard prone positioning, in which patients are turned to a full prone position (approximately 180 ) for at least 16 hours per day, following establish
Sponsors
Critical Care Unit
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 65 years of either gender, admitted to ICU with a diagnosis of moderate to severe ARDS according to Berlin or Kigali modification, and requiring invasive mechanical ventilation, will be included in the study
Exclusion criteria
Exclusion criteria: Refusal of consent from patient or legal guardian Contraindications to prone semi-prone positioning unstable spine pelvic long bone fractures recent abdominal or thoracic surgery raised intracranial pressure, open chest abdomen, facial/airway trauma Hemodynamically unstable patients (requiring escalating or high-dose vasopressor support). Severe arrhythmias or advanced heart failure. Pregnancy. Moribund patients with expected survival 24 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 72hrsTimepoint: Improvement in the oxygenation PaO2 FiO2 ratio was observed in both groups over a 72 hour period | — |
Secondary
| Measure | Time frame |
|---|---|
| Ventilatory parameters include compliance and driving pressure (calculated as plateau pressure minus PEEP). Hemodynamic parameters are assessed through mean arterial pressure and any vasopressor requirements. Other clinical outcomes to monitor include positioning-related complications (such as pressure sores and accidental tube displacement), ICU mortality, and ICU length of stay measured in days.Timepoint: Ventilatory parameters include compliance and driving pressure (calculated as plateau pressure minus PEEP). Hemodynamic parameters are assessed through mean arterial pressure and any vasopressor requirements. Other clinical outcomes to monitor include positioning-related complications (such as pressure sores and accidental tube displacement), ICU mortality, and ICU length of stay measured in days. | — |
Countries
India
Contacts
Public ContactVinod Kumar Srivastava
King Georges Medical University Lucknow
Outcome results
None listed