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Using Real-Time Eye Scanning During Radiation Treatment to Precisely Target and Treat Eye Surface Cancer: A Study Comparing the Scan Findings with Laboratory Tissue Analysis

Intraoperative optical coherence tomography guided plaque brachytherapy of ocular surface squamous neoplasia: a prospective study on real time tumour margin assessment and histopathological correlation. - NIL

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110731
Enrollment
20
Registered
2026-05-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C690- Malignant neoplasm of conjunctiva

Interventions

Intervention1: PLAQUE BRACHYTHERAPY: Patients with OSSN will undergo surgical excision with intraoperative OCT guidance for real-time assessment of tumour margins and depth. Adjuvant plaque brachyther

Sponsors

Dr. Rajendra Prasad Centre for Ophthalmic Sciences All India Institute of Medical Sciences (AIIMS)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged more than 18 years with a clinical diagnosis of ocular surface squamous neoplasia confirmed on cytology or biopsy Patients who are planned for surgical excision of OSSN and agree to study participation and follow up

Exclusion criteria

Exclusion criteria: Intraocular or orbital OSSN (AJC stage T 3 O R T4)

Design outcomes

Primary

MeasureTime frame
Tumour response to treatment (Slit-lamp biomicroscopy, ASOCT, Impression cytology), recurrence or relapse, side effects and correlation of iOCT findings with histopathological reports will be noted in follow-up Timepoint: 1 month, 2 months, 3 months, 4 months post-operatively.

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactVATSAL BUJETHIYA

Dr. Rajendra Prasad Centre for Ophthalmic Sciences All India Institute of Medical Sciences (AIIMS)

vatsal98@icloud.com8700439586

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026