None listed
Conditions
Interventions
Intervention1: PRF: Extraction socket will be filled with autologous platelet rich fibrin whose outcome will be assessed on postoperative day 3, 5 and day 10
Control Intervention1: Collagen sponge: Ex
Sponsors
Dr Ankit A Verma
Eligibility
Inclusion criteria
Inclusion criteria: 1)Systematically healthy individuals. 2) Patients indicated for surgical removal of impacted mandibular third molars. 3) Patients willing to participate and provide written informed consent.
Exclusion criteria
Exclusion criteria: 1)Patients with systemic diseases affecting wound healing. 2)Smokers and tobacco users. 3)Patients with acute infection at the surgical site. 4)Systematically compromised patients (ASA II onwards) 5)Patients on anticoagulant therapy or immunosuppressive drugs. 6)Pregnant and lactating women. 7)Deeply impacted 3rd molars (Position B/C and Class 2/3)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of soft tissue healing at the surgical site following mandibular third molar extraction, comparing autologous platelet-rich fibrin (PRF) with collagen sponge, using a standardized healing index.Timepoint: Day 3, Day 5 and Day 10 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Postoperative pain measured using a Visual Analog Scale (VAS) at specified time intervals 2)Facial swelling (edema) assessed using linear facial measurements 3)Trismus (mouth opening restriction) measured as maximum interincisal distance 4)Incidence of postoperative complications, including infection and dry socket (alveolar osteitis) 5)Patient-reported quality of recoveryTimepoint: Day 3, Day 5 and Day 10 | — |
Countries
India
Contacts
Public ContactDr Banibrata Lahiri
Kalinga Institute of Dental Sciences, KIIT Deemed to be university
Outcome results
None listed