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To compare precooled forms of anesthesia to see which works better for painful Lower Back Teeth

Comparative evaluation of 2 percent Lignocaine and 4 percent Articaine in precooled forms for success of inferior alveolar nerve block in Mandibular Molars with Symptomatic Irreversible Pulpitis - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110707
Enrollment
108
Registered
2026-05-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Endodontic treatment under influence of precooled forms of 4 percent articaine and 2 percent lignocaine: Endodontic treatment under influence of precooled forms of 4 percent articaine

Sponsors

JCD Dental college Sirsa haryana india
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients giving Informed consent for the study Healthy Patients Pre operative moderate to severe pain VAS scale greater than 54 mm Mature Mandibular first or second molars diagnosed with symptomatic irreversible pulpitis No peri apical radiolucency No prior history of root canal treatment

Exclusion criteria

Exclusion criteria: Patients not giving Informed consent for the study Patients whose age is less than 18 years and more than 50 years Patients allergic to local anesthesia or any other component of LA solution to be used in the study Patient having history of medicine intake including corticosteroids opioids NSAIDs tricyclic antidepressants or beta blockers in the past 12 hour Previously initiated or Endodontically treated teeth Drug abusers and alcoholics Pregnant patients Patients with neuropathic disorders chronic pain syndromes genetic and metabolic disorders inflammatory and autoimmune disorders

Design outcomes

Primary

MeasureTime frame
Anesthetic success rate No to mild pain indicated by 0 to 54 mm will be considered as successful anesthesia and moderate to severe pain 55 to 170 mm will be denoted as failureTimepoint: using VAS scale at baseline(immediate)

Secondary

MeasureTime frame
Pain on injection will be evaluated by the consultant endodontist immediately after the injection using HP VASTimepoint: using VAS scale at baseline(immediate)

Countries

India

Contacts

Public ContactDr Aanchal Garg

JCD dental college sirsa

singlaendo@gmail.com9996126025

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026