Health Condition 1: C00-D49- Neoplasms
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Sponsors
ACTREC, TMC
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients undergoing major elective oncologic upper GI/ hepatobiliary surgery, including hepatectomy, hepatic resection with bile duct resection, hilar cholangiocarcinoma surgery, gastrectomy, cholecystectomy, pancreaticoduodenectomy or major pancreatic resections, RP mass excisions. 2.Elective surgery with curative intent
Exclusion criteria
Exclusion criteria: 1.Emergency surgeries 2.Incomplete perioperative data required for E-PASS calculation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the predictive accuracy of the E-PASS Comprehensive Risk Score (CRS) for postoperative morbidity graded by the Clavien Dindo classification. Timepoint: 30 days | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the association of additional perioperative variables (6-minute walk test, serum albumin, BMI, history of cerebrovascular accident, and cancer stage) with postoperative morbidity.Timepoint: Upto 30 days;To develop a refined morbidity prediction model incorporating E-PASS components and additional independent predictorsTimepoint: Upto 30 days;To compare the discriminative performance of the refined model with the original E-PASS scoreTimepoint: Upto 30 days;To evaluate correlation between E-PASS CRS and postoperative morbidity survey (POMS) scores within 30 daysTimepoint: Upto 30 days;To assess the ability of E-PASS CRS to predict major postoperative complications (Clavien Dindo greater than equal to Grade III) within 30 days and comparative ability between different hepatobiliary surgeries.Timepoint: Upto 30 days | — |
Countries
India
Contacts
Public ContactDr Sarika J Chandran
Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)
Outcome results
None listed