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Study of Lung Infections after Mechanical Ventilation, Antibiotic Resistance, and Disease Markers in ICU Patients Using Advanced Techniques for Early Diagnosis and Effective Treatment

Characterization of Respiratory Microbiomes and Antimicrobial Resistance Patterns Using Metagenomics Approach, and Biomarker Profiling in Ventilator Associated Pneumonia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/05/110702
Enrollment
186
Registered
2026-05-20
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J958- Other intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified

Interventions

Intervention1: Nil: Nil

Sponsors

Indian Council of Medical Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Clinically defined VAP according to US CDC criteria Patient with at least one of the following - Fever - Leukopenia or leukocytosis - For adults altered mental status with no other recognized cause And at least two of the following - New onset of purulent sputum or change in character of sputum or increased respiratory secretions or increased suctioning requirements - Dyspnea or tachypnea or new onset or worsening cough - Rales or bronchial breath sounds - Worsening gas exchange or increased oxygen requirements or increased ventilator demand

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The study will identify etiological agents especially atypical or novel respiratory pathogens, antimicrobial resistance patterns, and diagnostic or prognostic biomarkers in ventilated associated pneumonia cases.Timepoint: NIL (The outcome measures will include various laboratory test results, which will be assessed only once)

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Ashwini M A

National Institute of Mental Health and Neurosciences (NIMHANS)

dr.ashwinishetty@gmail.com9448982763

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026