Health Condition 1: L989- Disorder of the skin and subcutaneous tissue, unspecified
Conditions
Interventions
Intervention1: Prospective Randomised Controlled Trial:Autologous Platelet rich plasma, autologous growth factor concentrate in chronic non-healing wounds: PRP, CGF, Normal saline dressing in chronic
Sponsors
ACS Medical Research InstituteAMRI
Eligibility
Inclusion criteria
Inclusion criteria: Age between eighteen and seventy five years Patients with chronic non healing wound of more than four weeks Of duration Aetiology includes diabetic foot ulcer Venous ulcer Pressure ulcer Post traumatic chronic wound Hemodynamically stable patients Platelet count normal Hemoglobin normal Patient willing to provide written informed consent
Exclusion criteria
Exclusion criteria: Malignant ulcers Osteomyelitis underlying the wound Active gangrene requiring amputation Acute infected wounds requiring emergency debridement Severe anaemia Thrombocytopenia Autoimmune disease Coagulopathy Patients on anticoagulants and anti platelets Uncontrolled diabetes Immunocompromised patients Severe peripheral arterial diseases Pregnantand lactating women Patients unwilling for follow up Patient with systemic sepsis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Meaning reduction in BWAT score from baseline to 4 weeksTimepoint: At baseline,1st week,2nd week,3rd week, 4th weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage reduction in wound are a Time to complete epithelization Reduction in VAS pain score Complication rateTimepoint: At baseline,1st week,2nd week,3rd week,4th week. | — |
Countries
India
Contacts
Public ContactSowmiyaa N
Sri Lalithambigai Medical college and hospital
Outcome results
None listed