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A Study Comparing Two Types of Nerve Blocks to Reduce Pain and Inflammation in Patients Undergoing Hip Replacement Surgery

A Randomized Comparative Trial comparing the Efficacy of Iliopsoas Space Block and Fascia Iliaca Block on Pain and Inflammatory Biomarkers (C-reactive protein and Procalcitonin) in Patients undergoing elective Total Hip Replacement Surgery - Nil

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110503
Enrollment
50
Registered
2026-05-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M87- Osteonecrosis Health Condition 2: S720- Fracture of head and neck of femur Health Condition 3: M16- Osteoarthritis of hip Health Condition 4: A180- Tuberculosis of bones and joints

Interventions

Intervention1: Iliopsoas Space Block: The Iliopsoas Space Block (IPSB) will be administered preoperatively under ultrasound guidance in a supine patient using strict aseptic precautions. A high-freque

Sponsors

Mathuradas Mathur Hospital Dr SN Medical College Jodhpur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age 60-80 years. 2. Male & Female genders. 3. ASA grade I-III. 4. Patients undergoing elective total hip replacement surgery.

Exclusion criteria

Exclusion criteria: 1. Any contraindications of spinal anaesthesia. 2. Raised levels of CRP & PCT at baseline. 3. Block failure. 4. Neurological deficiencies in lower limb. 5. Local infection at the puncture site for either block. 6. Alcohol dependence. 7. Chronic opioid dependence, or abuse. 8. Inability to cooperate. 9. Any history of cognitive disorders like Dementia or Delirium, Schizophrenia and Parkinson disease.

Design outcomes

Primary

MeasureTime frame
Comparison of pain scores (VAS 0-10) at rest and on movement at fixed intervals of baseline, 6 h, 12 h, 24 h, and 48 h postoperatively, Serum CRP and procalcitonin (PCT) levels at baseline, 6 h, 12 h, 24 h, and 48 h postoperatively, Comparison of Total opioid consumption in the first 24 hours and time to first rescue analgesia in patients receiving the FICB and IPSB BlocksTimepoint: Baseline, 6,12,24 and 48 hours postoperatively—

Secondary

MeasureTime frame
1. Analgesic Efficacy Total opioid consumption (24 48 hr) Time to first rescue analgesia 2. Functional Recovery Time to first ambulation Motor block assessment (e.g., Bromage scale) 3. Safety Profile Block-related complications 4. Physiological Parameters Hemodynamic stability (HR, BP trends) 5. Recovery & Inflammatory Response Length of hospital stay Biomarkers: C-reactive protein and ProcalcitoninTimepoint: 0 hr (baseline/post-op arrival) 2 hr 6 hr 12 hr 24 hr 48 hr—

Countries

India

Contacts

Public ContactDr Pramila Soni

Dr. SN Medical College Jodhpur

dr.ranbireshwar@gmail.com8696518297

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026