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Role of antibiotic prophylaxis in children with ureteric stent after pyeloplasty surgery

A randomized controlled trial evaluating the efficacy of continuous antibiotic prophylaxis in pediatric patients with ureteric stents following pyeloplasty - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110473
Enrollment
78
Registered
2026-05-12
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N130- Hydronephrosis with ureteropelvicjunction obstruction

Interventions

Intervention1: Group A: Administration of continuous antibiotic prophylaxis post-pyeloplasty uptil stent removal: Group A will include 35 patients who will receive continuous antibiotic prophylaxis of

Sponsors

Bangalore Medical College and Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Children between 0 to 16 years of age, undergoing open pyeloplasty with stent in-situ 2.Consent has been given by the parent or guardian, and assent from patients greater than 7 years of age.

Exclusion criteria

Exclusion criteria: 1.Patients with external stents, urethral catheters and nephrostomy tubes. 2.Patients with PUJO with any other congenital genitourinary tract abnormalities (vesicoureteral reflex, vesicoureteric junction obstruction, posterior urethral valves and neurogenic bladder). 3.Patients undergoing redo pyeloplasty.

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the frequency of febrile and asymptomatic culture positive urinary tract infections, with and without continuous antibiotic prophylaxis in pediatric patients with ureteric stents following pyeloplasty.Timepoint: 4 weeks

Secondary

MeasureTime frame
To identify patient demographic factors causing incidence of symptomatic UTI (age, gender, duration of stent left in situ, socioeconomic status, unilateral vs bilateral stent insertion & bowel habits of the child) & whether the use of CAP can be restricted to those that fall under those categories.Timepoint: 4 weeks

Countries

India

Contacts

Public ContactAayushka Lodha

Bangalore Medical College and Research Institute

lodhaaayushka2@gmail.com9901645500

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026