To assess the effect of two drugs as an additive for supraclavicular brachial plexus block on patients undergoing upper limb surgery.

A randomized comparative study to evaluate the analgesic effect of dexmedetomidine versus dexamethasone as an adjuvant to 0.5% bupivacaine in ultrasound guided infraclavicular brachial plexus block in upper limb surgeries in Department of Anesthesiology SMS Medical College Jaipur . - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/110445

Enrollment

Registered

2026-05-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ultrasound guided infraclavicular brachia plexus block in upper limb surgeries: To evaluate the analgesic effect of dexmedetomidine 50 micrograms as an adjuvant to 0.5% bupivacaine 20m

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for any elective upper limb surgeries requiring brachial plexus block 2. Patients willing to consent 3. Adult patients of either sex 4. Patients of ASAPS grade 1,2 4. Patients age between 18 and 60 years

Exclusion criteria

Exclusion criteria: 1. Allergy to study drug 2.Coagulopathy or bleeding disorders. 3. Severe cardiopulmonary disease 4.Neuropathy,vascular insufficiency of surgical limb 5. Infection at injection site 6.Patients on adrenergic antagonist or beta blocker or on long term analgesic.

Design outcomes

Primary

Measure	Time frame
Mean time of onset of complete sensory block ( minutes) Timepoint: 0,2,4,6,8,10,12,14,16,18,20 ,30 minutes	—

Secondary

Measure	Time frame
1. Mean time of onset of complete motor block (minutes) 2. Mean duration of motor block (minutes) 3. Mean of Numeric Pain Rating Score 4. Mean time to first rescue analgesia (minutes) 5. Proportion of cases having adverse effect if any in both groups as hypotension ,bradycardia , nausea and vomitting both intraoperative and postoperative. 6. Median of sedation scores 7. Mean systolic bp, mean diastolic bp, mean of mean bp, mean heart rate , mean oxygen saturation(SpO2)Timepoint: 0 , 5, 10, 15, 20, 25, 30, 45, 60, 75, 90minutes	—

Measure

Time frame

1. Mean time of onset of complete motor block (minutes) 2. Mean duration of motor block (minutes) 3. Mean of Numeric Pain Rating Score 4. Mean time to first rescue analgesia (minutes) 5. Proportion of cases having adverse effect if any in both groups as hypotension ,bradycardia , nausea and vomitting both intraoperative and postoperative. 6. Median of sedation scores 7. Mean systolic bp, mean diastolic bp, mean of mean bp, mean heart rate , mean oxygen saturation(SpO2)Timepoint: 0 , 5, 10, 15, 20, 25, 30, 45, 60, 75, 90minutes

—

Countries

India

Contacts

Public ContactDr Richa Sharma

SMS medical college and attached hospital jaipur

poonamkalra24@gmail.com9413416787

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026