A study to compare the effect of sevoflurane versus propofol on cerebral oxygen saturation in patients being operated for lumbar spine surgeries at Sawai Man Singh Medical College and hospital , Jaipur

A randomized comparative study to evaluate the effect of Sevoflurane versus Propofol on Cerebral Oxygen Saturation in patients undergoing Lumbar Spine Surgeries at Sawai Man Singh Medical College and Hospital, Jaipur - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/110373

Enrollment

Registered

2026-05-11

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: 7- Osteopathic

Interventions

Intervention1: Sevoflurane: Patients will receive sevoflurane 0.2 to 2 percent as maintenance anesthesia along with N2O:O2(50:50) titrated to maintain BIS score between 40-60.First the rsO2 values of

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing lumbar spine surgery 2. Patients with written informed consent 3. Either male or female patient 4. Patients aged 20 to 50 years 5. Patients belonging to American Society of Anaesthesiologists class 1 and 2

Exclusion criteria

Exclusion criteria: 1. Patients having massive hemodynamic perturbations intraoperatively 2. Patients with a history of allergy to study drug 3. Patients should not be a part of any other study

Design outcomes

Primary

Measure	Time frame
To assess and compare rsO2 intraoperatively at various time intervals between group A receiving sevoflurane and group B receiving propofol as maintenance anaesthetic agent respectively.Timepoint: at 5 mins interval throughout the surgery upto extubation	—

Secondary

Measure	Time frame
To assess and compare hemodynamic parameters (HR, SBP, DBP, MAP, SpO2) intraoperatively at various time interval between group A receiving sevoflurane and group B receiving propofol as maintenance anaesthetic agent . To assess and compare effect of prone position versus supine position on rsO2. To assess and compare the proportion of patients experiencing side effects if any. Timepoint: at 5 mins interval throughout the surgery upto extubation	—

Measure

Time frame

To assess and compare hemodynamic parameters (HR, SBP, DBP, MAP, SpO2) intraoperatively at various time interval between group A receiving sevoflurane and group B receiving propofol as maintenance anaesthetic agent . To assess and compare effect of prone position versus supine position on rsO2. To assess and compare the proportion of patients experiencing side effects if any. Timepoint: at 5 mins interval throughout the surgery upto extubation

—

Countries

India

Contacts

Public ContactDr Ankitha Ashok Shenoy

SMS Medical College and Hospital

drneelu13@gmail.com9782480455

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026