Health Condition 1: G250- Essential tremor
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: AI-assisted clinical monitoring: AI-assisted clinical monitoring using the Spiral Dx algorithm during clinic visits.
Spiral-Dx severity m
Sponsors
Indian Council of Medical Research (ICMR), New Delhi,
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age above 18 years 2) Diagnosis of essential tremor syndrome (ET, ET plus and dystonic tremor syndrome with hand tremor) by a movement disorder specialist according to the 2018 consensus criteria for classification of tremor 3) Moderate or severe ET defined as QUEST-SI more than 11.25
Exclusion criteria
Exclusion criteria: 1) Those who have no intact upper limbs (eg; above wrist amputation, severe weakness resulting in inability to grip pen) 2) Those who refuse consent to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome will be patient reported tremor related QOL as assessed by the QUEST scale at 12 months, which will be compared between the 2 arms.Timepoint: 0,3,6,9,12 months | — |
Secondary
| Measure | Time frame |
|---|---|
| QUEST subdomain indices: physical, psychosocial, communication, hobbies and work/financesTimepoint: 0,12 months;Clinician Global Impression of Change (CGIC)Timepoint: 0, 12 months;Patient Global Impression of Change (PGIC)Timepoint: 0, 12 months;Fahn-Tolosa-Marin Tremor Rating ScaleTimepoint: 0,3,6,9, 12 months;Edinburgh Handedness InventoryTimepoint: 0 months;Patient satisfaction with follow-up visits (on a visual analogue scale)Timepoint: 0, 12 months;Time taken for follow up assessmentsTimepoint: 0, 12 months;Adverse eventsTimepoint: 0, 12 months;Frequency of dosage changesTimepoint: 0, 12 months;Frequency of medication changesTimepoint: 0, 12 months | — |
Countries
India
Contacts
Public ContactDr Roopa Rajan
AIIMS
Outcome results
None listed