Effectiveness of Cocoa Bean Husk, Pomegranate Extract, and Chlorhexidine Mouthwashes Against Oral Bacteria in Children Aged 8 10 Years

Comparative Evaluation of Antimicrobial Efficacy of Cocoa Bean Husk Extract, Hydroalcoholic Extract of Pomegranate, and Chlorhexidine Mouthwashes Against Salivary Streptococcus mutans and Streptococcus salivarius in Children of Age 8-10 Years: An Ex Vivo Study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/110345

Enrollment

Registered

2026-05-11

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: Cocoa Bean Husk Extract Mouthwash: Cocoa bean husk extract mouthwash is a herbal oral rinse prepared from the outer shell (husk) of Theobroma cacao. It has gained attention in preventiv

Eligibility

Inclusion criteria

Inclusion criteria: Patients Of Age Between 8-10 Years. Patients With Positive, Definitely Positive Frankl Behaviour. Good Systemic Health, No Antibiotic Intake Within The Past 3 Weeks Before The Study Onset. No Use Of Orthodontic Or Prosthetic Appliances, No Xerostomia, No Periodontal Disease. Absence Of Active Caries In The Buccal and Lingual Surfaces Of Maxillary Right First Molar, Mandibular Left First Molar, Maxillary Left Lateral Incisor, Mandibular Right Lateral Incisor, Maxillary Right Central Incisor, And Mandibular Left Central Incisor Teeth.

Exclusion criteria

Exclusion criteria: Children With Special Care Needs, And Those With Intellectual Disabilities. Patients Undergoing Any Surgical Treatment Or Who Recently Underwent Topical Fluoride Application. Patients Having A History Of Allergy To Any Of The Components Of Mouthrinse Used. Patients Whose Parents, Guardians,Heads Of The Institution Have Not Consented For Permission.

Design outcomes

Primary

Measure	Time frame
Minimum Inhibitory Concentration, Minimum Bactericidal Concentration, Time kill assayTimepoint: 24 hours, 48 hours, 72 hours	—

Secondary

Measure	Time frame
NILTimepoint:	—

Countries

India

Contacts

Public ContactPRASANNA DAHAKE

MIDSR Dental College Latur

prasannadahake@gmail.com9545356010

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026