Health Condition 1: P073- Preterm [premature] newborn [other] Health Condition 2: P073- Preterm [premature] newborn [other]
Conditions
Interventions
Intervention1: Delayed cord clamping for 120seconds: In eligible stable preterm infants, umbilical cord clamping will be performed at 120 seconds after birth while maintaining standard neonatal care n
Sponsors
Seth GS Medical college and KEM hopsital
Eligibility
Inclusion criteria
Inclusion criteria: Inborn preterm infants born between 28 weeks 0 days and 36 weeks 6 days of gestation. Infants born from singleton or twin pregnancies (maximum two babies). Hemodynamically stable at birth, defined as effective breathing effort, heart rate more than 100 beats per minute, and not requiring immediate positive pressure ventilation. Written informed parental consent obtained before delivery.
Exclusion criteria
Exclusion criteria: Preterm infants with poor condition at birth, defined as depressed breathing effort, reduced muscle tone, or heart rate less than 100 beats per minute. Infants with major congenital anomalies diagnosed before birth. Intrauterine fetal death. Hydrops fetalis. Infants who underwent intrauterine procedures such as fetal blood transfusion, laser therapy, or amnioreduction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in middle cerebral artery mean blood flow velocity between delayed cord clamping at 60 seconds and 120 seconds in stable preterm infants.Timepoint: At 24 hours, 48 hours, and 72 hours after birth. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin levelTimepoint: At 24 hours after birth;HematocritTimepoint: At 24 hours after birth;Need for blood transfusionTimepoint: During hospital stay;Incidence of polycythemiaTimepoint: Within first 72 hours after birth;Serum bilirubin levelTimepoint: At 48 to 72 hours after birth;Incidence of intraventricular hemorrhageTimepoint: During hospital stay;Incidence of hypoglycemiaTimepoint: During hospital stay;Neurodevelopmental outcomeTimepoint: At 1 year of age | — |
Countries
India
Contacts
Public ContactAnitha Ananthan
SEth GS medical college and KEM Hospital
Outcome results
None listed