Endotracheal tube tolerance at the end of surgery

To Compare Intravenous Lignocaine with Lignocaine instillation through endotracheal tube to improve tube tolerance during extubation - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/110297

Enrollment

Registered

2026-05-10

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C785- Secondary malignant neoplasm of large intestine and rectum

Interventions

Intervention1: IV Lignocaine use during extubation: Duration of the study is one and a half year Control Intervention1: Lignocaine instillation during extubation to see tube tolerance: Direct Instilla

Eligibility

Inclusion criteria

Inclusion criteria: Open abdominal and thoracic surgeries under general anesthesia

Exclusion criteria

Exclusion criteria: H/O allergy to Lignocaine Anticipated difficult airway COPD Surgery duration more than 4 hours

Design outcomes

Primary

Measure	Time frame
to compare postoperative pain scoreTimepoint: 0hr,2hr,4hr,6hr,12hr,18hr,24hrs, after infiltration	—

Secondary

Measure	Time frame
To compare duration of analgesia To compare postoperative rescue analgesics requirements To compare hemodynamic To compare adverse effectTimepoint: 0hr,2hr,4hr,6hr,12hr,18hr,24hrs, after infiltration	—

Countries

India

Contacts

Public ContactAkshiteshkumar Manubhai Gameti

Gujarat Cancer and Research Institute affiliated to BJMC Ahmedabad

rnsbaps@gmail.com9825769907

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026