Health Condition 1: O- Medical and Surgical Health Condition 2: G935- Compression of brain Health Condition 3: G950- Syringomyelia and syringobulbia Health Condition 4: G952- Other and unspecified cord compression Health Condition 5: G936- Cerebral edema
Conditions
Interventions
Intervention1: CCeP block PLUS ESP block: Bilateral Ultrasound-Guided CCeP block at C2/C3 PLUS Bilateral ESP block at C6-C7.
CCeP: 10 mL of 0.2% Ropivacaine + 2 mg Dexamethasone per side.
ESP: 10 mL o
Sponsors
M S Ramaiah Medical College & Hospitals
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA Physical Status Grade I-III 2. Scheduled for elective posterior cranial fossa or CVJ surgery under general anaesthesia
Exclusion criteria
Exclusion criteria: 1. Severe bradycardia HR less than 45bpm or pathological arrhythmias 2. Patients on preoperative ventilator support 3. Quadriplegia 4. Pregnant or nursing mothers 5. Severe pulmonary disease, liver or renal disorders 6. Coagulopathy or ongoing anticoagulation 7. Infection at injection site 8. Allergy to local anaesthetics 9. Inability to comprehend NRS pain scoring 10. Intraoperative dorsal C1-C2 nerve resection or C2 ganglion resection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain intensity assessed by the Numerical Rating Scale at rest and with movement, measured atTimepoint: 0 immediate postoperative Baseline, 2, 4, 6, 8, 12, 24, 36, and 48 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Total intraoperative opioid fentanyl consumptionTimepoint: From begining to the end of surgery;Intraoperative hemodynamic stability: Heart Rate & Mean Arterial PressureTimepoint: At baseline before anesthesia,After the block every 5 minutes for the 15 minutes subsequently every 15 minutes from first 1 hour throughtout intraoperative period;Intraoperative Surgical Pleth IndexTimepoint: At baseline before anesthesia,After the block every 5 minutes for the 15 minutes subsequently every 15 minutes from first 1 hour throughtout intraoperative period;Time to first request for rescue analgesiaTimepoint: Post surgery in the post operative period;Interference with intraoperative neuromonitoring SSEP & or MEPTimepoint: Intraoperative period Baseline SSEP & or MEP After anesthesia induction & at the time of patient positioning, second set of SSEPs & MEPs will be obtained after admistration of the blocks but before surgical incision & Serial SSEP & MEP checks will be performed at the surgeons request during instrumentation, correction, & skin closure;Blood stress markers ABG pH, RBS, Lactate lvels measured atTimepoint: baseline before surgical incision & 1 hour post-extubation or anesthesia;Total patient satisfaction score using 10-point questionnaireTimepoint: at 48 hours post surgery;Time to mobilization sitting and walkingTimepoint: From point of post surgery;Total amount of opioids consumedTimepoint: in 48 hours post surgery;Occurence of any Complications hypotension, bradycardia, LAST, respiratory compromiseTimepoint: Throughout intraoperative perod from the begning till the end of anesthesia | — |
Countries
India
Contacts
Public ContactDr Pramod Kalgudi
M S Ramaiah Medical College
Outcome results
None listed