Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Magnesium sulphate pretreatment with rocuronium bromide (0.6 mg/kg): Intravenous magnesium sulphate administered as pretreatment followed by intravenous rocuronium bromide at a dose of
Sponsors
Ayushi Goyal
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing cardiac surgeries. Patients giving informed written consent. Patients coming in to ASA grade II,III. Patients coming in to Mallampati grade I,II. Patients with an Inter-Incisor distance of atleast 3cm. Patients with BMI in the normal range (18.5-24.9).
Exclusion criteria
Exclusion criteria: Patients with known allergies to Magnesium sulphate or Rocuronium bromide. Patients with a history of neuromuscular disorders. Patients with severe Mitral stenosis and Aortic stenosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To assess and compare onset time of two different doses of Rocuronium bromide between two groups. Timepoint: time interval between administration of intubating dose of rocuronium bromide and loss of last twitch on tof | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess & compare the difference in favourable intubating conditions between the groups: Laryngoscopy , vocal cord position & reaction to insertion of the tracheal tube & cough inflation.Timepoint: During intubation;To assess & compare the difference in the duration of action between the groups.Timepoint: appearance of first twitch of TOF from the onset;To assess & compare the requirement of rocuronium bromide per/kg/hour during surgery between the groups.Timepoint: At the end of surgery | — |
Countries
India
Contacts
Public ContactDr Anjum Saiyed
SMS medical college
Outcome results
None listed