Health Condition 1: C509- Malignant neoplasm of breast of unspecified site Health Condition 2: C500- Malignant neoplasm of nipple and areola
Conditions
Interventions
Intervention1: Tablet Memantine for anxiolysis in patients undergoing mastectomy: 2o mg tablet peroral preoperatively evening before surgery
Control Intervention1: tablet clonazepam given preoperative
Sponsors
Sanjay Gandhi post graduate institute of medical sciences LUCKNOW
Eligibility
Inclusion criteria
Inclusion criteria: 1) Female patients aged between 30 to 65 years posted for elective mastectomy for breast cancer. 2) ASA grade 1 and 2
Exclusion criteria
Exclusion criteria: 1) Patients with psychiatric or mental illness 2) Patients having serious liver/kidney disease 3) Drug addicts or alcoholics 4) Pregnant female 5) Patients on antidepressants/antianxiety drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)Anxiety score in preoperative period before shifting to operation theatre using the State Trait Anxiety Inventory (STAI)Timepoint: at the time of shifting the patient to Operation Theatre | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Anxiety in post operative period for three days. 2) Total amount of rescue analgesia administered to patient as calculated from PCA pump for three days postoperatively. 3) Postoperative sleep quality as assessed using the Pittsburg sleep quality index(PSQI) for three days. Timepoint: for three days postoperatively at interval of 24 hours | — |
Countries
India
Contacts
Public Contactshilpi verma
Sanjay Gandhi post graduate institute of medical sciences, LUCKNOW
Outcome results
None listed