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A clinical study to compare three different antimicrobial solutions to be used inside the milk teeth of children aged 4 to 8 years for infection removal and healing.

Comparative clinical evaluation of various endodontic irrigants in Lesion Sterilization and Tissue Repair (LSTR) therapy in primary teeth: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110218
Enrollment
60
Registered
2026-05-08
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: 10.2% Curcumin intracanal irrigant : The intervention study group is termed as G3 (Group 3) where Curcumin (10.2%) intracanal irrigant, 10 mL for 1 minute, single application during LS

Sponsors

SGT University Gurugram Haryana
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Presence of any one in each category: CLINICAL CRITERIA:- 1. Deep carious lesion with pulp exposure 2. Signs of irreversible pulpitis or non-vitality 3. Pulpotomy treated tooth showing signs of radicular pulpal necrosis or irreversible pulpitis. RADIOGRAPHIC CRITERIA: 1. Discontinuity of lamina dura 2. Periapical and inter-radicular radiolucency 3. Furcation involvement

Exclusion criteria

Exclusion criteria: Presence of any one of the following: 1. Children with systemic illness. 2. Non-restorable teeth. 3. Children with an allergy to the study materials.

Design outcomes

Primary

MeasureTime frame
Clinical success defined by absence of pain, swelling, sinus/fistula, and tenderness on percussionTimepoint: 01 month 03 months 06 months 09 months

Secondary

MeasureTime frame
Radiographic healing (reduction in radiolucency, improvement in lamina dura, bone regeneration) Root resorption status (physiologic/pathologic)Timepoint: 01 month 03 months 06 months 09 months

Countries

India

Contacts

Public ContactDr Satakshi Bhattacharjee

Shree Guru Gobind Singh Tricentenary University

shalu.verma@sgtuniversity.org9871720820

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026