Health Condition 1: B159- Hepatitis A without hepatic coma
Conditions
Interventions
Intervention1: Nacetycystine: NAC will be given intravenously as
21-hour regimen in 3 doses with cumulative dose of 300 mg/kg over 21 hours
(initial loading dose of 150 mg/kg over one hour, followed b
Sponsors
Dr Dheeraj Dasariya
Eligibility
Inclusion criteria
Inclusion criteria: Aged between 5to 15 years Parents willing to participate in the study Hepatitis A virus antibody +ve serology
Exclusion criteria
Exclusion criteria: Aged more than 16 years Prior history of NAC administration Wilson disease Drug induced hepatitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in serum ALT levels from baseline (Day 0) to Day 7 after initiation of N-acetylcysteine therapy in children aged 5 15 years with hepatitis A.Timepoint: 7 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Time in days to normalization of serum ALT,AST Levels assessed from day 0 to day 14 or dischargeTimepoint: 14 day | — |
Countries
India
Contacts
Public ContactDr Ghanshyam Das
Outcome results
None listed