Health Condition 1: K02- Dental caries
Conditions
Interventions
Intervention1: Restoration and pulp Therapy: Restoration and pulp Therapy will be done after baseline saliva sample collection.
Control Intervention1: Levels of salivary biomarkers before treatment: L
Sponsors
Dr Mausam kumari
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria for Group 1 children Children aged between 3 - 6 years Children diagnosed with caries, having ICDAS score of 1 3 Parents/guardians provide informed consent Inclusion criteria for Group 2 children Children aged between 3 - 6 years Children diagnosed with at least one carious tooth, having ICDAS score of 4 - 6 Parents/guardians provide informed consent
Exclusion criteria
Exclusion criteria: Exclusion criteria for both the groups Children with systemic diseases or conditions affecting salivary flow Use of antibiotics or anti-inflammatory drugs within last 3 months Presence of oral mucosal diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the quantitative change in salivary concentrations of fibronectin, statherin, and cathelicidin LL-37 measured before and after dental treatment in children with early childhood caries.Timepoint: Baseline (pre-treatment) and post-treatment follow-up after 2 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of salivary biomarker levels between ICDAS-based groups 1.Correlation between biomarker levels and caries severity (ICDAS scores) 2.Within-group analysis of pre- and post-treatment changes 3.Assessment of clinical improvement following treatmentTimepoint: Baseline (pre-treatment) and post-treatment follow-up after 2 months | — |
Countries
India
Contacts
Public ContactDr Vabitha Shetty
A B Shetty memorial institute of dental sciences
Outcome results
None listed