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A study to see which cleaning solution works best to remove infection from childrens milk teeth

COMPARATIVE EVALAUTION OF ANTIBACTERIAL EFFICACY OF FOUR DIFFERENT ROOT CANAL IRRIGANTS IN DISINFECTION OF PRIMARY MOLARS: A RANDOMIZED CONTROLLED TRIAL - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110162
Enrollment
75
Registered
2026-05-06
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Group I :17 percent Liquid EDTA Group II:6 pecent Citric acid Group III: 9 percent Etidronic acid Group IV :5 percent Glycolic acid : Paricipant will be randomly allocated into four int

Sponsors

Dr Dilpreet Kaur Gumber
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Children aged between 5-9 years requiring pulpectomy in primary molars 2 Teeth with at least two-third of root length remaining 3 Teeth with clinical diagnosis of necrotic pulp or irreversible pulpitis 4 Teeth without signs of internal or external root resorption 5 Absence of pathological mobility 6 Frankl behavior rating 3 or 4 7 Teeth with restorable crown structure 8 Teeth with no evidence of pathological root resorption exceeding one third of root length 9 Children who are medically Healthy (ASA I or II)

Exclusion criteria

Exclusion criteria: 1 Teeth with advanced root resorption or mobility (Grade II/III) 2 Teeth with previous endodontic treatment or calcified & severely curved canals 3 Children with history of antibiotic therapy within last 2 weeks 4 Children with known allergy or hypersensitivity to any of irrigant solutions used in study 5 Medically compromised children 6 Non restorable crown structure 7 Parents /guardian not willing to provide written informed consent 8 Frankl behavior rating (1or 2)

Design outcomes

Primary

MeasureTime frame
Reduction in microbial load (CFU/ml) of Enterococcus faecalis and Candida albicans in infected primary molars following root canal irrigation.Timepoint: Pre-irrigation and immediately post-irrigation (after completion of final irrigation procedure)

Secondary

MeasureTime frame
Comparative evaluation of antibacterial efficacy among different root canal irrigants.Timepoint: Pre-irrigation and Immediately post-irrigation.

Countries

India

Contacts

Public ContactDr Brij Kumar

Rungta college of Dental sciences and Research,Bhilai

brij220787@gmail.com8827800994

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026