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Comparison of Gum Inflammation Markers in Patients with Zirconia and PEEK Dental Crowns

Comparison and Correlation of Inflammatory Cytokines (IL-1beta , IL-6) in Gingival Crevicular Fluid with Gingival Health in Zirconia and PEEK Crowns A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110123
Enrollment
30
Registered
2026-05-06
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Zirconia Crowns: Inflammatory cytokines evaluation. Modified gingival Index assessment. Intervention2: PEEK Crowns: Inflammatory cytokines evaluation. Modified gingival Index assessment

Sponsors

Prabhat Kumar Lohchab
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient requiring a single full coverage posterior crowns with root canal treated tooth. Systemically healthy individual. Probing pocket depth less than 3 mm at study tooth.

Exclusion criteria

Exclusion criteria: Patient with any systemic disease affecting periodontal health. Current or former smoker or tobacco users. Patient on medications that influence periodontal status or cytokine level. Pregnant or lactating women. Patient with poor plaque control or inability to maintain oral hygiene.

Design outcomes

Primary

MeasureTime frame
Difference in levels of IL-1beta and IL-6 in Gingival Crevicular Fluid between Zirconia and PEEK crown groupsTimepoint: At baseline and 3 weeks—

Secondary

MeasureTime frame
nilTimepoint: nil—

Countries

India

Contacts

Public ContactNeha Jain

Manav Rachna Dental College

nehajain.sds@mrei.ac.in9818095434

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026