Comparing use amino acid infusion along with routine intravenous fluid during brain tumor surgery

Effect of intraoperative infusion of amino acid in addition to the routine fluid management in patient undergoing supratentorial tumour surgery - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/110096

Enrollment

Registered

2026-05-06

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C719- Malignant neoplasm of brain, unspecified Health Condition 2: C710- Malignant neoplasm of cerebrum, except lobes and ventricles Health Condition 3: C711- Malignant neoplasm of frontal lobe Health Condition 4: C714- Malignant neoplasm of occipital lobe Health Condition 5: C718- Malignant neoplasm of overlappingsites of brain Health Condition 6: C713- Malignant neoplasm of parietal lobe Health Condition 7: C712- Malignant neoplasm of temporal lobe

Interventions

Intervention1: Group A: Group A will receive a balanced amino acid infusion(AMINOVEN 10 %)at a dose of 1.5 g/kg in addition to the routine fluid administration @ institutional protocol Control Interve

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient posted for supratentorial surgery,2.Age group between 18 to 60 years,3.ASA 1-2,4.Body Mass Index 25-30 kg/metter square

Exclusion criteria

Exclusion criteria: 1.Refused to participate in the study,2.Allergy to any studied medication,3.Severe cardiac, Hepatic or Renal insufficiency,4.Any uncontrolled hypertensive or diabetic patient,5.pregnancy,6.patient undergoing psychiatric treatment.7 Surgery duration less than 4 hours

Design outcomes

Primary

Measure	Time frame
To evaluate the effects of infusion of amino acid in addition to routine fluid administration in patients undergoing supratentorial surgery, as assessed by levels of IL-6 and CRPTimepoint: IL-6 and CRP will be assessed preoperatively , 4 hourly , 8 hourly , 24 hourly	—

Secondary

Measure	Time frame
patient intraoperative hemodynamic parameter , GCS and temperature will also be assessed Timepoint: 1.Intraoperative Hemodynamics and temperature will be assessed every 15 minutes 2.The GCS will be assessed at 30 min, 1 hour, 2 hour, 4 hour, 8 hour and 24 hour post extubation	—

Countries

India

Contacts

Public ContactDr Somsubhra Pal

Institute of Medical Sciences

drsandeepscb@gmail.com8960919866

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026