Pain Control After Breast Surgery: Comparing Thoracic Epidural and Thoracic Paravertebral Block Techniques

A Prospective Randomized Clinical Study of Analgesic Efficacy of Thoracic Epidural Versus Ultrasound-Guided Thoracic Paravertebral Block with 0.25% Levobupivacaine in Breast Surgery - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/110041

Enrollment

Registered

2026-05-05

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Thoracic Paravertebral Block: Ultrasound-guided thoracic paravertebral block at T4 T6 level using 0.25% Levobupivacaine Dose/Volume: 20 mL (single-shot, preoperative) Control Intervent

Eligibility

Inclusion criteria

Inclusion criteria: Age18 yrs to 65 yrs ASA grades I and II Normotensive patients BMI less than 30 Kg/m2 Valid informed consent

Exclusion criteria

Exclusion criteria: Patient refusal Patients having a history of significant cardio-respiratory, neurological, psychiatric, or neuromuscular disorders. Local skin site infections. Bleeding diathesis. History of allergic reactions to anesthetic drugs. Spinal deformities

Design outcomes

Primary

Measure	Time frame
To evaluate postoperative pain at fixed intervals using visual analogue scale (VAS) Timepoint: 0,2,4,6,12 and 24 hours post operatively	—

Secondary

Measure	Time frame
1.To compare the total opioid consumption in the first 24 hours postoperatively. 2.Incidence of post-op nausea & vomiting 3.Post-operative patient satisfaction.Timepoint: First 24 hours postoperatively	—

Countries

India

Contacts

Public ContactChristie Angel Lakra

Rajendra Institute of Medical Sciences

dr.ladhulakra007@gmail.com07779853657

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026