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Helping people with bleeding-related knee problems strengthen their thigh muscles: testing how combining gentle exercise with restricted blood flow training can work better together.

Augmented quadriceps rehabilitation in hemophilic knee arthropathy: investigating the synergistic effects of blood flow restriction training and low intensity exercise - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/110022
Enrollment
22
Registered
2026-05-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D66- Hereditary factor VIII deficiency Health Condition 2: D67- Hereditary factor IX deficiency

Interventions

Intervention1: Blood Flow Restriction training(BFRT) with low intensity exercise: BFRT was given for the quadriceps muscle with 40% restriction of arterial blood flow and low intensity exercise corres

Sponsors

Amra Nizar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age: 18 years and above Gender: males and females Radiological evidence of haemophilic knee arthropathy using Pettersson scoring

Exclusion criteria

Exclusion criteria: Any previous surgery of the hip and knee joint.15 Venous insufficiency. Deep vein thrombosis.

Design outcomes

Primary

MeasureTime frame
Quadriceps muscle strength using Modified Sphygmomanometer Test (MST) measured in mmHgTimepoint: At baseline and at after 6 weeks—

Secondary

MeasureTime frame
Quadriceps muscle mass using inch tape in cmTimepoint: At baseline and at after 6 weeks;Quadriceps muscle activation using surface electromyography (sEMG) measured in % of normalizationTimepoint: At baseline and after 6 weeks;Average number of joint bleeds the patient experienced in the knee joint in a monthTimepoint: At baseline—

Countries

India

Contacts

Public ContactDr TG Tilak Francis

Krupanidhi College of Physiotherapy

tilakfrancis@gmail.com9444341940

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026