Skip to content

Quality initiative study to reduce the usage of antibiotics among the neonates getting admitted in NICU

A Quality improvement initiative to reduce unnecessary antimicrobial usage in neonatal intensive care unit. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/05/110012
Enrollment
500
Registered
2026-05-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B998- Other infectious disease

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Himalayan Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All neonates getting admitted to the NICU

Exclusion criteria

Exclusion criteria: 1. Neonates with major congenital malformations 2. Referred from other centres after three days of antibiotic exposure 3. Neonates with incomplete or missing records

Design outcomes

Primary

MeasureTime frame
The primary outcome will be the reduction in the rate of antibiotic usage among NICU admissions, calculated as: Antibiotic utilization ratio= Total monthly Days of therapy (DOT) Total monthly patient days Timepoint: The primary outcome will be the reduction in the rate of antibiotic usage among NICU admissions, calculated as: Antibiotic utilization ratio= Total monthly Days of therapy (DOT) Total monthly patient days All admitted neonates getting admitted to NICU will be included and will be monitored for antibiotic usage up till discharge. AUR will be assessed monthly.

Secondary

MeasureTime frame
Reduction in median antibiotic days for both term and preterm neonate Incidence of culture-positive sepsis for both term and preterm neonate All-cause NICU mortality rates before and after intervention Timepoint: ALL NEONATED GETTING ADMITTED TO NICU WILL BE INCLUDED AND WILL BE OBSERVED TILL DISCHARGE.AN INITAIL INTERVENTION OF 6 MONTHS FOLLOWED BY 12 MONTHS OF SUSTENENCE PHASE (TOTAL DURATIOM-18 MONTHS)

Countries

India

Contacts

Public ContactDr Saikat Patra

Department of Neonatology, Himalayan Institute of Medical Sciences, Dehradun, Uttarakhand - 248016

nrndrsharma541@gmail.com8931022355

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026