Skip to content

Comparison of two bupivacaine types for safer spinal anesthesia in heart disease patients undergoing anorectal surgery

Clinical efficacy of isobaric and hyperbaric bupivacaine in patients with ischemic heart disease undergoing anorectal surgery under subarachnoid block: A prospective randomised comparative clinical study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/109950
Enrollment
68
Registered
2026-05-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Isobaric Bupivacaine: Group I will receive isobaric bupivacaine, and Group II will receive hyperbaric bupivacaine administered through Subarachnoid Block under standard aseptic precauti

Sponsors

Himani Gautam
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA 2 and 3 with documented ischemic heart disease, scheduled for elective anorectal surgery providing written informed consent.

Exclusion criteria

Exclusion criteria: Patient refusal. Contraindication to spinal anaesthesia. Known allergy to spinal anaesthesia. Severe valvular heart disease, triple vessel disease, uncontrollable hypertension, or ongoing arrhythmias

Design outcomes

Primary

MeasureTime frame
To compare block characteristics in terms of: Onset of sensory block Highest dermatomal level achieved Duration of sensory block Onset, grade and duration of motor blockTimepoint: Onset of sensory block

Secondary

MeasureTime frame
To compare the intraoperative hemodynamic parameters (heart rate, blood pressure, ECG changes) To compare the incidence of perioperative complications (e.g., hypotension, bradycardia, arrhythmias, nausea, vomiting, urinary retention, post-dural puncture headache). To compare total dose of rescue analgesic in postoperative period upto 24 hrs To compare the patient satisfaction Timepoint: 1,3,5,10,15 minutes, then every 15 minutes upto 2 hours

Countries

India

Contacts

Public ContactProf Shefali Gautam

King Georges Medical University Lucknow

drshefaligautam@gmail.com9559468440

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026