Comparison of standard and individualized human milk feeding in preterms

Comparison of Targeted Fortification of human milk(to achieve a protein intake of 3.5-4 gm/kg/day) with Standard Fortification on short-term outcomes in preterm neonates (26-30+6 weeks gestation): A Randomized Control Trial - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/05/109934

Enrollment

Registered

2026-05-04

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P073- Preterm [premature] newborn [other]

Interventions

Intervention1: Targeted Fortification: In the intervention group, targeted fortification of the feeds with an available fortifier will be started, once the feed volume reaches 180 ml/kg/day, to reach

Eligibility

Inclusion criteria

Inclusion criteria: Estimated gestational age between 26 weeks and 30 weeks 6 days based on best obstetric estimate Tolerating standard-fortified human milk feeds of atleast 150 ml/kg/day for a minimum duration of 72 hrs

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Weight gain velocity at 36 weeks post menstrual ageTimepoint: Weight gain velocity at 36 weeks post menstrual age	—

Secondary

Measure	Time frame
Time to regain birth weight Linear growth velocity Head circumference growth velocity Incidence of feed intolerance Incidence of NEC, BPD, ROP All cause mortality during hospital stay Duration of hospital stay Incidence of extrauterine growth restriction at 40 weeks post menstrual ageTimepoint: Daily till death/ discharge	—

Countries

India

Contacts

Public ContactSahil Bansal

Lady Hardinge Medical College

drsnangia@gmail.com9810838181

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026