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Intact umblical cord milking instead ofimmediate cord clamping in preterm neonates requiring resuscitation

Comparison of intact umbilical cord milking with immediate cord clamping on short term neonatal outcomes in non-vigorous preterm neonates (28-34 Weeks Gestation) - A Randomized Control Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/05/109888
Enrollment
90
Registered
2026-05-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: P84- Other problems with newborn

Interventions

Intervention1: Intact umblical cord milking: An approximately 20 cm length of the umbilical cord will be ensured. The cord will be grasped firmly between the thumb and forefinger, and about 20 cm of b

Sponsors

Lady Hardinge Medical College, New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Preterm neonate between 28+0 to 34+6 days based on best obstetric estimate who do not cry immediately after birth.

Exclusion criteria

Exclusion criteria: 1. Major congenital anomalies (antenatally diagnosed or visible at birth) 2. Known fetal anaemia or hydrops fetalis 3. Twin pregnancy 4. Placental abruption 5. Umbilical cord avulsion or other cord abnormalities preventing cord milking

Design outcomes

Primary

MeasureTime frame
e composite outcome of death or severe IVH (grade III or IV) or NEC (stage IIB or more on modified Bell staging) or retinopathy of prematurity (ROP) any stages or bronchopulmonary dysplasia.Timepoint: Death /discharge/36 weeks PMA whichever is later

Secondary

MeasureTime frame
1. Proportion of babies requiring resuscitation - PPV for 60 sec or more. 2. Mean APGAR score at 5, 10 minutes of life 3. Mean Cord pH 4. Severe IVH (grade III or IV) 5. NEC (stage IIb or more on modified Bell staging) 6. Retinopathy of prematurity (ROP) any stages 7. Bronchopulmonary dysplasia (BPD) 8. Mean haemoglobin at 24 hrs of life 9. Proportion of babies requiring transfusion during hospital stayTimepoint: Death /discharge/36 weeks PMA whichever is later

Countries

India

Contacts

Public ContactDr Priti Yadav

Lady Hardinge Medical College, New Delhi

drsnangia@gmail.com9810838181

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026