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Laser vs Coblation assisted inferior turbinate reduction: Which is better

Effectiveness of CO2 laser vs coblation assisted reduction of inferior turbinate in cases of significant inferior turbinate hypertrophy : A Randomised Control Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/109846
Enrollment
64
Registered
2026-04-30
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J343- Hypertrophy of nasal turbinates

Interventions

Intervention1: Inferior turbinate reduction: Using carbon dioxide laser once for 30 mins Intervention2: Inferior turbinate reduction: Using coblation Control Intervention1: Inferior turbinate reductio

Sponsors

Nandini
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with unilateral/ bilateral inferior turbinate hypertrophy causing persistent nasal obstruction despite at least 6 weeks of regular nasal corticosteroid therapy.

Exclusion criteria

Exclusion criteria: Patient unwilling to consent Previous nasal or turbinate surgery. Deviated nasal septum requiring septoplasty. Presence of nasal polyps, tumors, or other obstructive nasal lesions. Systemic diseases such as uncontrolled diabetes mellitus, hypertension, or autoimmune disorders. Known hypersensitivity to anesthesia or any material used in the surgical procedure. Patients unwilling or unable to follow-up for the postoperative evaluation schedule.

Design outcomes

Primary

MeasureTime frame
To measure and compare between the groups: The efficacy of CO2 laser assisted inferior turbinate reduction versus Coblation assisted Inferior turbinate reduction using Nasal obstruction symptom evaluation score (NOSE score) Improvement in endoscopic scoring of turbinate size pre and post surgery Timepoint: To measure and compare between the groups: The efficacy of CO2 laser assisted inferior turbinate reduction versus Coblation assisted Inferior turbinate reduction using Nasal obstruction symptom evaluation score (NOSE score) Improvement in endoscopic scoring of turbinate size pre and post surgery at day 7, day 30, and 3 month mark—

Secondary

MeasureTime frame
To compare post operative pain & recovery by Visual Analog Scale (immediate post operatively, 1 week & 1 month post surgery) for CO2 laser & Coblation assisted turbinectomy respectively Endoscopic evaluation of mucosal healing at 1 month & 3 months postoperatively by assessment of crusting or synechiae formation. Nasal mucociliary clearance rate estimation & comparison in both groups. To measure the inferior turbinate volume on NCCT PNS preoperatively & to determine correlation between NOSE scores & Endoscopic scores. Timepoint: Day 7, day 30 & 3 months—

Countries

India

Contacts

Public ContactNandini

Department of ENT, Second Floor B block, OPD building, AIIMS Bathinda

sarthaknamdini@gmail.com7814995490

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026