Can Carduus Marianus Help Reduce High Cholesterol? Insights from Cell Studies and Clinical Research

ANTI-HYPERLIPIDEMIC EFFECTS OF CARDUUS MARIANUS IN 3T3-L1 ADIPOCYTES USING CELL LINE STUDIES AND CLINICAL TRAIL. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/109834

Enrollment

Registered

2026-04-30

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E785- Hyperlipidemia, unspecified

Interventions

Intervention1: CARDUUS MARIANUS: Carduus Marianus mother tincture: 5 drops, three times daily / Carduus Marianus 6C: 40-size globules, three times daily for 5 weeks Control Intervention1: HOMOEOPATHIC

Eligibility

Inclusion criteria

Inclusion criteria: 1.Cases with hyperlipidemia with age of 20-65years from both sexes(28) 2.Cases with Total cholesterol level more than 210 mg/dl

Exclusion criteria

Exclusion criteria: 1.Individuals with a history of chronic alcohol consumption and long-term tobacco smoking. 2.Pregnant ladies and lactating mothers. 3. The LDL/HDL ratio is greater than 5. 4. Case with Total cholesterol level more than 300mg/d

Design outcomes

Primary

Measure	Time frame
1.CELL LINE STUDY TITLE: Action of Carduus marianus on lipid metabolism in 3T3-L1 adipocyte cell line: Modulation of PPAR pathway analyzed by FACS. DURATION: Minimum of one month 2.2.Clinica StudyTitle : Reduction in serum total cholesterol level Description : Serum total cholesterol final value-serum total cholesterol base line value Interval : 3 monthsTimepoint: 1.CELL LINE STUDY Duration : 3 months	—

Measure

Time frame

1.CELL LINE STUDY TITLE: Action of Carduus marianus on lipid metabolism in 3T3-L1 adipocyte cell line: Modulation of PPAR pathway analyzed by FACS. DURATION: Minimum of one month 2.2.Clinica StudyTitle : Reduction in serum total cholesterol level Description : Serum total cholesterol final value-serum total cholesterol base line value Interval : 3 monthsTimepoint: 1.CELL LINE STUDY Duration : 3 months

—

Secondary

Measure	Time frame
comparison of theapeutic effectiveness of carduus marianus and constitutional homoeopathic medicineTimepoint: after 1 year	—

Countries

India

Contacts

Public ContactDr MUHISINA A MANAF

Government Homoeopathic Medical College Karaparamba Kozhikode

munshidnt@gmail.com9946784552

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026