Health Condition 1: C719- Malignant neoplasm of brain, unspecified Health Condition 2: D330- Benign neoplasm of brain, supratentorial
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologist physical status class I- III Both gender Age 18-65 years undergoing Neurosurgical procedures Surgeries in supine position Patient or legal heir consent
Exclusion criteria
Exclusion criteria: 1. Surgeries in lateral and prone position 2. Age 65 years 3. Drug allergy to Propofol 4. Refusal to consent by patient or legal heir 5. Patients who are intubated and on mechanical ventilation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlation between TTE and TEE with different depth of anesthesia by assessing Transmitral pulsed wave doppler velocity and tissue Doppler velocity (lateral and septal)Timepoint: a) Before induction (T1) b) After induction of anesthesia at BIS 40-50 (T2) c) After induction of anesthesia at BIS 60-70 (T3) d) After induction of anesthetia at BIS 70-80 (T4) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Ejection fraction 2) Aortic valve area based measurement of stroke volume and cardiac output in 2 chamber and 4 chamber LV long axis view 3) Vital parameters- Heart Rate(HR), Invasive Blood Pressure(MAP) 4) Bispectral Index(BIS), Pulse Pressure Variation (PPV)Timepoint: a) Before induction (T1) b) After induction of anesthesia at BIS 40-50 (T2) c) After induction of anesthesia at BIS 60-70 (T3) d) After induction of anesthetia at BIS 70-80 (T4) | — |
Countries
India
Contacts
Sree Chitra Tirunal Institute For Medical Sciences and Technology