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Study to evaluate efficacy of dexmedetomidine vs magnesium sulphate to facilitate awake flexible video laryngoscopy guided nasotracheal intubation in adult patients with anticipated difficult airway posted under general anaesthesia

EFFICACY OF DEXMEDETOMIDINE AND MAGNESIUM SULPHATE TO FACILITATE AWAKE FLEXIBLE VIDEO LARYNGOSCOPY GUIDED NASOTRACHEAL INTUBATION IN ADULT PATIENTS WITH ANTICIPATED AIRWAY DIFFICULTY: A PROSPECTIVE RANDOMISED DOUBLE-BLIND STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/109750
Enrollment
60
Registered
2026-04-29
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S024- Fracture of malar, maxillary and zygoma bones Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: AWAKE FLEXIBLE VIDEOLARYNGOSCOPIC GUIDED NASOTRACHEAL INTUBATION WITH DEXMEDETOMIDINE: TO COMPARE RAMSAY SEDATION SCORE, GRADING OF DISCOMFORT, COUGH SEVERITY, INTUBATING CONDITIONS, HE

Sponsors

Dr. EDIGA VAMSHI KRISHNA GOUD
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 18 and 65 years of either sex belonging to American Society of Anesthesiologists (ASA) physical status I and II scheduled for elective surgical procedures under general anaesthesia with anticipated difficult airway requiring awake flexible video laryngoscopic nasotracheal intubation.

Exclusion criteria

Exclusion criteria: 1. Known hypersensitivity to study drugs 2. History of epistaxis 3. Patients with nasal pathology 4. Pregnant Patients 5. Coagulopathies, bleeding disorders 6. Mental disability/delirium 7. Polytrauma 8. Cardiovascular disease

Design outcomes

Primary

MeasureTime frame
To compare level of sedation using Ramsay sedation score between groups.Timepoint: ASSESS RAMSAY SEDATION SCORE JUST BEFORE PASSING ENDOTRACHEAL TUBE OVER VOCAL CORDS—

Secondary

MeasureTime frame
1. To compare grading of discomfort, cough severity and intubating conditions between the two groups.Timepoint: AT THE TIME OF INTUBATION;2. To compare hemodynamic parameters (Pulse rate, Blood pressure) and oxygen saturation between two groups. Timepoint: AT TIME OF INTUBATION, 5 MINUTES AFTER INTUBATION;3. To study the adverse effects between two groupsTimepoint: EVERY HOUR THROUGH INTRAOPERATIVE AND POSTOPERATIVE PERIOD UPTO 48 HOURS—

Countries

India

Contacts

Public ContactDr C SUNIL

Government medical college, Kadapa

drchiruvellasunil@gmail.com9441988164

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026