A Study To Compare The Effects Of Adding Midazolam Versus Buprenorphine To Ropivacaine For Spinal Anaesthesia In Patients Undergoing Surgeries Below the Navel

Comparison Of Effects of Intrathecal Midazolam And Intrathecal Buprenorphine As Adjuvant To Hyperbaric Ropivacaine In Patients Undergoing Infraumbilical Surgeries-A Randomized Controlled Study - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/109736

Enrollment

Registered

2026-04-29

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intrathecal Route Midazolam 2mg As Adjuvant To Ropivacaine 0.75% 2.8ml: Acts On GABA A Receptor Loacted In Substantia Gelatinosa Inhibitting Neurotrasmission And Reducing Pain Signal Tr

Eligibility

Inclusion criteria

Inclusion criteria: Patients Willing To Give Informed Written Consent Patients With ASA Grade 1 And 2 Patients Scheduled For Infraumbilical Surgeries Under Subarachnoid Block.

Exclusion criteria

Exclusion criteria: Patients Belonging To ASA Grade 3 4 5 Patients With Neurological Cardiovascular Respiratory Renal And Hepatic Derrangement Patients With History Of Hypersensitivity To Local Anaesthesia Benzodiazepines Patients Having Absolute Contraindication For Spinal Anaesthesia Pregnant patient undergoing cesarian section.

Design outcomes

Primary

Measure	Time frame
onset Of sensory Block Timepoint: Baseline Of Onset Of Sensory Block	—

Secondary

Measure	Time frame
Duration of Anealgesia Heamodynamic Parameter Sedation Adverse EffectTimepoint: Baseline 1 min 2 min 3 min 4 min 5 min every 5 min till 30 min every 10 min till 180 min Immediate post op period evry 2 hr for 6 hr 12 hr 24 hr	—

Countries

India

Contacts

Public ContactDr Chiranthkumar G Nelogal

Banglore Medical College And Research Institute,

chiranth.nelogal@gmail.com9686325147

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026