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Predictive model for safe extubation

Predictive model for safe extubation after posterior fossa surgery incorporating pupillary light reflex as a surrogate for brainstem function - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/109712
Enrollment
68
Registered
2026-04-29
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G988- Other disorders of nervous system

Interventions

Intervention1: Nil: Nil

Sponsors

Akanksha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients Undergoing elective or emergency posterior fossa surgery Intubated postoperatively and planned for extubation during icu stay Availability of quantitative pupillometry within 2 hours before extubation

Exclusion criteria

Exclusion criteria: Pre existing severe brain stem injury or known unreactive pupils prior to surgery Pupillometry unavailable or technically infeasible due to ocular trauma or facial swelling Patients who are tracheostomized, do not undergo extubation or die before extubation decision Re intubation for non neurological reasons

Design outcomes

Primary

MeasureTime frame
Successful extubation, defined as no requirement for re intubation or mechanical ventilatory support within 72hours of initial extubationTimepoint: 72 hours

Secondary

MeasureTime frame
Decreased ICU length of stay, duration of mechanical ventilation, post extubation complicationsTimepoint: 72 hours;Discharge disposition or in hospital mortalityTimepoint: 72 hours

Countries

India

Contacts

Public ContactVinod Srivastava

King George Medical University

brijeshmbbs@gmail.com8953497291

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026