None listed
Conditions
Interventions
Intervention1: L-PRF plug: The L- PRF plug immediately placed on the experimental side 1st premolar extraction socket
Control Intervention1: PLACEBO: PLACEBO
Sponsors
ANJU JINENDRA A
Eligibility
Inclusion criteria
Inclusion criteria: Systemically healthy patients with Class II div 1 or Class I b maxillary protrusion with relatively well-aligned arches or mild crowding or open bite.Post pubertal as assessed by CVMI stage more than 5, requiring therapeutic bilateral symmetric extraction of premolars Healthy oral and systemic condition Normal platelet count
Exclusion criteria
Exclusion criteria: Patients who refuse /Non cooperative to receive therapy with Autologous L-PRF Patients with platelet disorders Immunocompromised patients History of previous orthodontic treatment Patients taking medications that could interfere with orthodontic tooth movement (NSAIDS, cortisone, hormones, anticoagulants) Smoking Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measuring the amount of tooth movement -To evaluate and compare the rate of orthodontic tooth movement with and without Autologous L- PRF placed in therapeutic extraction sockets after mechanical loading.Timepoint: Just before the extraction (T0), 1 week (T1),2 weeks (T2),4 weeks (T3),8 weeks (T4) | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of Anchorage loss of maxillary molar before & after retraction while placing autologous L -PRF Timepoint: T0 5 Months T2 7 months ;Evaluation of Angle of Rotation of maxillary canine before & after retraction while placing autologous L -PRFTimepoint: T0 5 Months T2 7 Months | — |
Countries
India
Contacts
Public ContactDr Roopesh R
PMS College of Dental science and Research
Outcome results
None listed