FindTrial
Sign In

Checking Heart Function Risks in Elderly Patients Before Knee Replacement Surgery Using Routine Exams and Machine Tests

CARDIO-TKR: CARDIAC AUTONOMIC DYSFUNCTION RISK STRATIFICATION USING INTEGRATED CLINICAL AND AUTOMATED AUTONOMIC ASSESSMENT IN THE GERIATRIC POPULATION UNDERGOING TOTAL KNEE REPLACEMENT SURGERY A PROSPECTIVE OBSERVATIONAL STUDY - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2026/04/109690
Enrollment
110
Registered
2026-04-29
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G909- Disorder of the autonomic nervoussystem, unspecified

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Dr Abhishek verma
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)patients of either sex of age more than or equal to 65 years 2)scheduled for primary unilateral total knee replacement surgery 3)ASA Grade 1 to 3

Exclusion criteria

Exclusion criteria: 1)patient refusal or inability to provide informed consent 2)documented autonomic neuropathy unrelated to aging or chronic illness 3)permanent pacemaker or arrhythmias interfering with heart rate variability interpretation 4)recent (less than 6 months) myocardial infarction aor cerebrovascular accident 5)severe cognitive impairment precluding performance of autonomic tests

Design outcomes

Primary

MeasureTime frame
Evaluate cardiac autonomic dysfunctionTimepoint: Baseline 2 weeks—

Secondary

MeasureTime frame
Intraoperative hemodynamic instability,immediate post operative complicationsTimepoint: 18months—

Countries

India

Contacts

Public ContactDr Vinita Singh

King George medical university

drvinitasingh70@gmail.com9415080782

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026