anaesthesia Drugs in PECS block for modified radical mastectomy.

Evaluate the efficacy of PECS block as standalone anaesthesia technique for modified radical mastectomy- A Prospective interventional study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/109657

Enrollment

Registered

2026-04-28

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: PECS I AND PECS II Block using 0.5% bupivacaine with dexamethasone with ketamine and dexmedetomidine infusion for sedation.: Ultrasound guided PECS I and PECS II block will be administe

Eligibility

Inclusion criteria

Inclusion criteria: Patients classified as American Society of Anaesthesiologists (ASA) physical status I, II OR III.

Exclusion criteria

Exclusion criteria: 1. Patient refusal to participate or undergo regional anesthesia. 2.Known allergy or hypersensitivity to local anesthetics or study drugs (Bupivacaine, dexamethasone, ketamine, dexmedetomidine,lignocaine). 3.Infection at the block site or local skin pathology. 4. Coagulopathy or bleeding disorders 5.History of severe cardiovascular or respiratory instability contraindicating sedation or regional anesthesia. 6. Neurological disorders affecting pain perception or sensory mapping. 7. Patients on chronic opioid or sedative use, which may influence block efficacy. 8.Inability to understand or communicate pain scores reliably (e.g., severe cognitive impairment). 9.BMI more than 35 kg per m , as excessive adiposity may interfere with block performance or ultrasound visualization

Design outcomes

Primary

Measure	Time frame
To assess the success rate of modified radical mastectomy surgeries completed under ultrasound guided PECS block with sedation without conversion to general anaesthesia. To assess intraoperative haemodynamic stability and to document complications or adverse events related to PECS block and sedation.Timepoint: Before block, just after block ,then every 5 min. till 30 mins and then 1 hrly till the end of surgery	—

Measure

Time frame

To assess the success rate of modified radical mastectomy surgeries completed under ultrasound guided PECS block with sedation without conversion to general anaesthesia. To assess intraoperative haemodynamic stability and to document complications or adverse events related to PECS block and sedation.Timepoint: Before block, just after block ,then every 5 min. till 30 mins and then 1 hrly till the end of surgery

—

Secondary

Measure	Time frame
To assess postoperative pain scores using the Numerical Rating Scale To assess total analgesic consumption during the first 24 hours after surgeryTimepoint: To observe postoperative pain scores using NRS at 30mins 1,2,4,6,8,10,12,16,20 and 24 hours	—

Countries

India

Contacts

Public ContactDr Kanta Bhati

Sardar Patel Medical College

drkantabhati67@gmail.com9413466688

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026