Health Condition 1: J219- Acute bronchiolitis, unspecified
Conditions
Interventions
Intervention1: 21 HFNC: Initiating HHHFNC with 21 percent fraction of inspired oxygen
Control Intervention1: 40 HFNC: initiating HHHFNC with 40 percent fraction of inspired oxygen
Sponsors
Arvind Krishna Dhakshinmurthy
Eligibility
Inclusion criteria
Inclusion criteria: Age between 1 month and 24months with Presence of respiratory distress is defined as presence 1)Tachypnea with Respiratory rate : 1month to 2months more than 60 per min 3months to 12months more than 50per min 13months to 24months morethan 40per min (or) 2)increased work of breathing - Chest indrawing or retractions (subcostal or intercostal or suprasternal retraction) or Nasal flaring
Exclusion criteria
Exclusion criteria: 1)Children with hemodynamic instability requiring inotropes 2)Known congenital heart disease 3)Craniofacial malformation 4)Altered sensorium 5) Apnea 6)Bradycardia 7)Cyanosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the incidence of primary treatment escalation and secondary treatment escalationTimepoint: baseline (0 minutes), 60 minutes, 120 minutes, 180 minutes, 240 minutes, 300 minutes, and 360 minutes, followed by 6-hourly assessments for up to 96 hours or until HFNC is successfully weaned, whichever occurs earlier | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the rate of HFNC failureTimepoint: 96hours;To determine the time required for resolution of respiratory distress,Timepoint: 96 hours;To compare the change in ROX index between the two groups at predefined time points baseline 0 hours 6 hours 12 hours 18 hours 24 hours36 hours and 48 hoursTimepoint: 96 hours;To determine the length of PICU stay and total hospital stay in both groups.Timepoint: 96 hours | — |
Countries
India
Contacts
Public ContactArvind krishna Dhakshinamurthy
Mehta Multispecialty Hospital
Outcome results
None listed