Benefits of a Pre-surgery Exercise and Nutrition Program in Patients Undergoing Pancreatic Surgery

Clinical Benefits of Prehabilitation in Patients Undergoing Pancreatic Resection (PREPARE) : A Randomized Controlled Trial - PREPARE

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/109575

Enrollment

Registered

2026-04-28

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Prehabilitation: 1. PERT (Pancreatic Enzyme Replacement Therapy) by supplementing Pancreatin 25000 IU BD 2.Targeted Physiotherapy a. 4000 minimum step target per day b.resistance band

Eligibility

Inclusion criteria

Inclusion criteria: Age more than 18 years of age ASA less than or equal to 3 Patients who are planned for major pancreatic resection

Exclusion criteria

Exclusion criteria: Patients who undergo Enucleation, Debridement, Multivisceral resection (except Distal pancreatosplenectomy)

Design outcomes

Primary

Measure	Time frame
Rate of major postoperative complications Clavien Dindo grade more than or equal to 3Timepoint: Post operative day 4,7,14,21,28,30	—

Secondary

Measure	Time frame
Clinically relevant postoperative pancreatic fistula (CR-POPF) (Grades B C). Delayed gastric emptying (DGE) (Grades A C; clinically relevant B C reported separately). Post Pancreatectomy Hemorrhage Postoperative pulmonary complications defined by standard clinical/radiologic criteria. Overall complication rate (all Clavien Dindo grades) within 30 days. Length of postoperative hospital stay (days) from index admission until discharge. Any ICU admission & duration (days) 90 day mortality. Readmission rateTimepoint: Post operative day 4,7,14,21,28,30	—

Measure

Time frame

Clinically relevant postoperative pancreatic fistula (CR-POPF) (Grades B C). Delayed gastric emptying (DGE) (Grades A C; clinically relevant B C reported separately). Post Pancreatectomy Hemorrhage Postoperative pulmonary complications defined by standard clinical/radiologic criteria. Overall complication rate (all Clavien Dindo grades) within 30 days. Length of postoperative hospital stay (days) from index admission until discharge. Any ICU admission & duration (days) 90 day mortality. Readmission rateTimepoint: Post operative day 4,7,14,21,28,30

—

Countries

India

Contacts

Public ContactDr Peeyush Varshney

AIl India Institute of Medical Sciences, Jodhpur

drpeeyushvarshney@gmail.com9929069007

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026