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Comparison of IV Dexmedetomidine and Nalbuphine for ease of positioning and postoperative Analgesia during spinal Anesthesia.

Comparative Evaluation of IV Dexmedetomidine and IV Nalbuphine for Ease of Positioning and Postoperative Analgesia during Spinal Anesthesia in Lower Limb Surgeries. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/109546
Enrollment
120
Registered
2026-04-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: V008- Accident on other pedestrian conveyance Health Condition 2: X19- Contact with other heat and hot substances Health Condition 3: V234- Motorcycle driver injured in collision with car, pick-up truck or van in traffic accident Health Condition 4: V899- Person injured in unspecified vehicle accident Health Condition 5: V440- Car driver injured in collision with heavy transport vehicle or bus in nontraffic accident Health Condition 6: X04- Exposure to ignition of highly flam

Interventions

Intervention1: IV Dexmedetomidine: Inj. Dexmedetomidine 1mcg/kg IV diluted to 10 ml normal saline and will be infused over 10 minutes. Control Intervention1: IV Nalbuphine: Inj. Nalbuphine 0.2mg/kg I

Sponsors

Drashti C Bagul
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists Physical Status I/II Elective Lower Limb surgeries under spinal anesthesia with duration of less than 150 minutes

Exclusion criteria

Exclusion criteria: Patient Refusal ASA Grade III/IV Patients Known allergy to any of study drug History of chronic analgesic use, history of alcohol/drug abuse, Opioid dependence or psychiatric illness Cardiovascular instability, congestive heart failure, hypovolemic shock, severe liver/renal disease, coagulation abnormality pregnant women Any contradiction to spinal anesthesia patient receiving calcium channel blockers/angiotensin-converting enzymes (ACE)inhibitors/beta blockers/clonidine

Design outcomes

Primary

MeasureTime frame
1.To compare ease of positioning score 2.To determine postoperative VAS ScoreTimepoint: 1.After 10 minutes of giving study Drug 2.Upto 12 hours from giving study Drug—

Secondary

MeasureTime frame
1.To compare university of michigan sedation between two groups 2.To assess the intraoperative hemodynamic parameters 3.To compare pin prick score 4.To evaluate the patient satisfaction score 5.To determine any adverse effects Timepoint: 1.Upto 120 minutes 2.Upto 120 minutes 3.At the time of giving spinal Anesthesia by 4 point scale 4.After completion of surgery 5 point of likert scale 5.Upto 12 hours—

Countries

India

Contacts

Public ContactKhyati C jethva

PDU Medical College ,Rajkot

baguldrashti1592@gmail.com9879466622

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026