A study to compare pain relief in the first 24 hours after surgery using a nerve block with and without additional medicines in children undergoing arm surgery

Comparison of dexamethasone and dexmedetomidine as adjuncts with ropivacaine in axillary brachial plexus block in pediatric patients undergoing upper limb surgery a randomized comparative study - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/109525

Enrollment

Registered

2026-04-28

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Q709- Syndactyly, unspecified Health Condition 2: Q681- Congenital deformity of finger(s)and hand Health Condition 3: Q699- Polydactyly, unspecified Health Condition 4: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine + Ropivacaine: Ropivacaine 0.5% with dexmedetomidine 0.5 mcg/kg for axillary brachial plexus block. Single perineural dose administered at the time of block. Interventio

Eligibility

Inclusion criteria

Inclusion criteria: Children aged one to ten years ASA physical status one and two undergoing upper limb surgeries under general anesthesia with axillary brachial plexus block

Exclusion criteria

Exclusion criteria: Patients with parental refusal Patient with age less than one year or age more than ten year Allergy to study drugs Coagulopathy Infection at block site Neurological or neuromuscular disorders Developmental delay or previous surgery on the same limb

Design outcomes

Primary

Measure	Time frame
Total postoperative analgesic consumption in first 24 hoursTimepoint: At 1, 2, 4, 6, 8, 12 and 24 hours postoperatively	—

Secondary

Measure	Time frame
Pain scores using FLACC and visual analogue scaleTimepoint: One two four six twelve and twenty four hours postoperatively;Time to first rescue analgesiaTimepoint: Within twenty four hours postoperatively;Hemodynamic parameters heart rate mean arterial pressure oxygen saturationTimepoint: Baseline intraoperative and postoperative period up to twenty four hours;Sedation level using Ramsay sedation scaleTimepoint: One two four six twelve and twenty four hours postoperatively;Incidence of adverse events such as nausea vomiting bradycardia hypotensionTimepoint: Intraoperative and postoperative period up to twenty four hours	—

Measure

Time frame

Pain scores using FLACC and visual analogue scaleTimepoint: One two four six twelve and twenty four hours postoperatively;Time to first rescue analgesiaTimepoint: Within twenty four hours postoperatively;Hemodynamic parameters heart rate mean arterial pressure oxygen saturationTimepoint: Baseline intraoperative and postoperative period up to twenty four hours;Sedation level using Ramsay sedation scaleTimepoint: One two four six twelve and twenty four hours postoperatively;Incidence of adverse events such as nausea vomiting bradycardia hypotensionTimepoint: Intraoperative and postoperative period up to twenty four hours

—

Countries

India

Contacts

Public ContactDr Monika

King Georges Medical University

sateeshverma24@gmail.com73798 37390

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026