Health Condition 1: T885- Other complications of anesthesia
Conditions
Interventions
Intervention1: Magnesium Sulphate: Magnesium sulphate 40 mg/kg diluted in 10 ml of 0.9% normal saline, administered intravenously slowly over 10 minutes, completed approximately 1.5 minutes before ind
Sponsors
Self
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 65 years of either gender, belonging to ASA physical status I and II, scheduled for elective surgeries under general anaesthesia requiring succinylcholine for tracheal intubation, willing to provide written informed consent.
Exclusion criteria
Exclusion criteria: Patients with ASA physical status III and above; patients undergoing emergency surgeries; patients with known hypersensitivity or contraindication to magnesium sulphate; patients with pre-existing neuromuscular or musculoskeletal disorders; patients receiving calcium channel blockers; patients with severe renal, hepatic, cardiac or respiratory disease; patients who have received analgesics within 24 hours prior to surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and severity of succinylcholine-induced muscle fasciculations, assessed immediately after administration of succinylcholine using Foster s four-point grading scale (0 3).Timepoint: Incidence and severity of succinylcholine-induced fasciculations, assessed immediately after administration of succinylcholine during induction of anaesthesia. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence and severity of postoperative myalgia, assessed up to 24 hours after surgery using White s four-point grading scale (0 3).Timepoint: Post-operative period (0, 6, 12 and 24 hours) | — |
Countries
India
Contacts
Public ContactDr Nikki Sunil Jain
Smt.Bhikhiben Kanjibhai Shah Medical Institute and Research Center
Outcome results
None listed