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comparison of erector spinae plane block versus pectoral nerve block in breast cancer surgery patients for immune response and pain relief

comparative evaluation of immunological impact (using neutrophil to lymphocyte and platelet to lymphocyte ratios) and analgesic effect of erector spinae plane block versus pectoral nerve block in breast cancer surgery patients - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2026/04/109416
Enrollment
80
Registered
2026-04-27
Start date
Unknown
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: erector spinae plane block: Ultrasound guided erector spinae plane block at T5 level with 30 ml of 0.25 percent ropivacaine Control Intervention1: Pectoral nerve blocks 1 and 2: Ultraso

Sponsors

Guru Gobind Singh Medical College and hosital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Female patients aged 18-65 years of age undergoing breast cancer surgeries belonging to American society of Anesthesiologists grade I and II with BMI between 18.5-24.9kg/m2 and giving informed written consent for procedure

Exclusion criteria

Exclusion criteria: Those with known hematological malignancies, preg nant females, patients on chronic treatmentwith steroids or immunosuppressants, patients/attendant refusal,with evidence of ac tive infection in the planned block area, existing coagulopathy, emergency cases, severe organ failure and with history of local anaesthetic allergy were excluded from the study.

Design outcomes

Primary

MeasureTime frame
To compare and evaluate immunological impact of Erector spinae plane block (ESPB) versus Pectoral Nerve Block (PEC) using Neutrophil to lymphocyte ratio (NLR) in breast cancer surgery patientsTimepoint: baseline preoperative 1 hour post operative 24 hour postoperative

Secondary

MeasureTime frame
To compare and evaluate immunological impact of Erector spinae plane block (ESPB) versus Pectoral Nerve Block (PEC) using Platelet lymphocyte ratio (PLR) in breast cancer surgery patients. 2.To compare and evaluate analgesic effect of both blocks in terms of postoperative analgesic consumption, pain scores and side effects if any. Timepoint: platelet to lymphocyte ratio at baseline preoperative 1 hour post operative 24 hour postoperative post operative pain scores at 0,2,6,12,24 hours

Countries

India

Contacts

Public ContactRajvir Kaur

Guru Gobind Singh Medical College and Hospital Faridkot

docrajvirkandhola32@gmail.com08557879837

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 11, 2026