A study to compare herbal and licorice lollipops with a normal (placebo) lollipop to see how they affect tooth germs and plaque in children with age 4-8 years

Comparative Evaluation of the Effect of Polyherbal, Licorice and Placebo Lollipops on Streptococcus Mutans Count and Plaque Accumulation in Children : A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2026/04/109358

Enrollment

Registered

2026-04-27

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Licorice Lollipop: Licorice lollipop shows potent antibacterial activity against Streptococcus mutans. The presence of bioactive compounds such as glycyrrhizin and glabridin contributes

Eligibility

Inclusion criteria

Inclusion criteria: 1 Children with high caries risk by using American Academy of Pediatric Dentistry Caries Risk Assessment tool. 2 Children presenting with visible dental plaque (plaque index score more than or equal to 1). 3 No antibiotic or antimicrobial mouthwash use in the past 4 weeks.

Exclusion criteria

Exclusion criteria: 1 Allergy to herbal products. 2 Children undergoing orthodontic treatment. 3 Systemic illness affecting salivary flow. 4 Uncooperative children.

Design outcomes

Primary

Measure	Time frame
There is some statistically significant difference in salivary Streptococcus mutans levels and plaque accumulation among high caries risk children using polyherbal , licorice and placebo lollipops.Timepoint: 2 years , 2 month	—

Secondary

Measure	Time frame
There is no statistically significant difference in salivary streptococcus mutans levels & plaque accumulation among high caries risk children using polyherbal , licorice & placebo lollipops.Timepoint: 2 years , 2 month	—

Countries

India

Contacts

Public ContactRuchita Walakate

Maharashtra Institute of Dental Sciences and Research ,Dental College , Latur

ruchitawalakate2324@gmail.com8421076952

Outcome results